Multiomics

Multiomics

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PU.1-driven enrichment enables microglia profiling from frozen brain tissue using the high-throughput Smart-seq3xpress method

by admin | Aug 15, 2025 | News

Single-cell transcriptomics has revealed the central role of microglia in brain development, homeostasis, and disease, particularly in the context of neuroinflammation. While single-cell RNA-sequencing enables targeted microglial analysis from fresh tissue, studying...

Recent Advances in Understanding the Pathophysiology of Fabry Disease

by admin | Jun 30, 2025 | News

Fabry disease is an inherited metabolic disease that is caused by an abnormal accumulation of sphingolipids, including globotriaosylceramide (Gb-3), in lysosomes. Patients with Fabry disease have reduced or absence of an enzyme called α-galactosidase, which...

Recent Posts

  • Martina Živná received the Czech Minister of Health Award for Medical Research and Development in 2025 for her successful project Identification and Characterization of Genetic Factors of Hereditary Tubulointerstitial Kidney Disease II.
  • Multiomics Workshop in BIOCEV
  • Extracellular vesicles as precision therapeutics for psychiatric conditions: targeting interactions among neuronal, glial, and immune networks
  • Novel structure motif for the selective inhibition of TET1 protein based on perimidines
  • The potential of exosomes in regenerative medicine and in the diagnosis and therapies of neurodegenerative diseases and cancer

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The MULTIOMICS_CZ project is supported by programme Johannes Amos Comenius, Ministry of Education, Youth and Sports of the Czech Republic,
ID Project CZ.02.01.01/00/23_020/0008540 – Co-funded by the European Union.

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