About project
Collaboration and Project Goals
The project is based on close cooperation between research organizations and the application sector. The partnership consists of five research entities – three academic institutions (Charles University, IMIC, IBIT) and two application partners (AffiPro and GeneSpector).
Main objectives and benefits of the project:
- Systematic interconnection and development of the research and application potential of participating groups and organizations
- Building long-term partnerships with the application sector
- Identifying biological correlates of diseases and developing new diagnostic, preventive, and therapeutic approaches
- Developing and implementing innovative methods in bioinformatics and multi-omics analyses (DNA, RNA, proteins, metabolites)
- Establishing a functionally complementary platform of multi-omics technologies
- Creating new diagnostic and therapeutic procedures
Project duration
January 1, 2025 – December 31, 2028 (sustainability until December 31, 2032)
Main recipient
Charles University
Project lead
Prof. Ing. Stanislav Kmoch, CSc.
Multi-omics platform for identifying biological correlates of diseases and developing new diagnostic, preventive, and therapeutic approaches (MULTIOMICS_CZ)
Registration number: CZ.02.01.01/00/23_020/0008540
Identification code: EH23_020/0008540
The project is funded by the Programme Johannes Amos Comenius, Call No. 02_23_020 – Intersectoral Cooperation.
Project Description
- Establishment of a multi-omics technology platform at BIOCEV to accelerate research on genetic and biological correlates of disease.
- Connection of teams and infrastructure across partners to standardize and scale analyses of DNA, RNA, proteins, and metabolites.
- Integration of multi-omics data using advanced bioinformatics.
- Translation of results into healthcare applications supported by shared protocols and quality assurance.
- Access to instrumentation and expertise.
- Fostering of staff development and training opportunities.
- Pilot studies with application-sector partners to ensure reproducibility, comparability, and validation of findings.
Project Impact
- Creation of an environment that enables, connects, and develops research and application potential across institutions.
- Long-term partnerships and cooperation with the application sphere subjects.
- More robust discovery of disease correlates and mechanisms.
- Acceleration of diagnostic, preventive, and therapeutic development.
- Improved readiness for clinical translation of research outputs.
- Reduction of duplication and higher data quality through shared platforms and governance.
- Shortened timelines from concept to pilot implementation.
- Expanded access to advanced technologies across partners.
- Support for talent development and staff training.
- Stimulation of follow-on collaborations and funding.
- Positioning of the consortium as a national hub for multi-omics innovation with healthcare relevance.
Project Objectives
- Strengthen cooperation between research organizations and the application sector.
- Build a comprehensive multi-omics platform at BIOCEV.
- Connect and develop participating groups for collaboration.
- Standardize sample handling and analytical workflows across partners.
- Implementation of innovative bioinformatics for integrative analysis across omics layers.
- Establish a shared portfolio of validated methods, benchmarking datasets, and training modules.
- Formalize partnerships beyond the core consortium to co-develop use cases and verify clinical/pre-clinical utility.
- Define responsibilities, data sharing, and routes to joint development through collaboration agreements.