Mechanistic Modelling of Recessive Disease through Allelic Integration of Variant Effects

by admin | Oct 16, 2025 | Publications

Unpublished preprint Çubuk H, Plech M, Aslanzadeh V, et al (2025) bioRxiv 2025.08.15.670494. https://doi.org/10.1101/2025.08.15.670494

PU.1-driven enrichment enables microglia profiling from frozen brain tissue using the high-throughput Smart-seq3xpress method

by admin | Oct 16, 2025 | Publications

Unpublished preprint Dostalova D, Abaffy P, Rohlova E, et al (2025) bioRxiv 2025.08.11.669607. https://doi.org/10.1101/2025.08.11.669607

De novo heterozygous variants in EHMT2 genocopy Kleefstra syndrome via loss of G9a methyltransferase activity

by admin | Oct 16, 2025 | Publications

Unpublished preprint Hnízda A, Martinez-Delgado B, Sanchez-Ponce D, et al (2025) bioRxiv 2025.09.25.678439. https://doi.org/10.1101/2025.09.25.678439

Preparation and characterization of flow reactors for the validation of biological drugs

by admin | Oct 16, 2025 | Publications

Diploma thesis Kordík J (2025) Univerzita Karlova, Přírodovědecká fakulta Katedra biochemie, 2025.

Single-nucleus transcriptome analysis provides new insights into B chromosome elimination in sorghum

by admin | Oct 7, 2025 | News

B chromosomes (Bs) are supernumerary entities found in many plant species, with some exhibiting tissue-specific elimination. In Sorghum purpureosericeum, extensive level of the B chromosome elimination occurs during embryogenesis. It progresses quickly and affects...