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Interaction of Selected Anthracycline and Tetracycline Chemotherapeutics with Poly(I:C) Molecules

by admin | Apr 15, 2025 | News

Despite the natural ability of the immune system to recognize cancer and, in some patients, even to eliminate it, cancer cells have acquired numerous evading mechanisms. With the increasing knowledge and focus shifting from targeting rapidly proliferating cells with...

Extracellular vesicles as precision therapeutics for psychiatric conditions: targeting interactions among neuronal, glial, and immune networks

by admin | Apr 8, 2025 | News

The critical role of the immune system in brain function and dysfunction is well recognized, yet development of immune therapies for psychiatric diseases has been slow due to concerns about iatrogenic immune deficiencies. These concerns are emphasized by the lack of...

Lysosomal Storage-Independent Fabry Disease Variants with α-Galactosidase A Misprocessing-Induced ER Stress and the Unfolded Protein Response

by admin | Mar 20, 2025 | News

Clinical findings in Fabry disease have classically been attributed to loss-of-function variants in the GLA gene that result in α-galactosidase A deficiency, intracellular accumulation of globotriaosylceramides and clinical manifestations. However, over time,...

The potential of exosomes in regenerative medicine and in the diagnosis and therapies of neurodegenerative diseases and cancer

by admin | Mar 13, 2025 | News

Exosomes, nanosized extracellular vesicles released by various cell types, are intensively studied for the diagnosis and treatment of cancer and neurodegenerative diseases, and they also display high usability in regenerative medicine. Emphasizing their diagnostic...

Genetic Testing in Adults over 50 Years with Chronic Kidney Disease: Diagnostic Yield and Clinical Implications in a Specialized Kidney Genetics Clinic

by admin | Feb 20, 2025 | News

Genetic causes of chronic diseases, once considered rare in adult-onset disease, now account for between 10 and 20% of cases of chronic kidney disease (CKD). Confirming a genetic diagnosis can influence disease management; however, the utility of genetic testing in...
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Recent Posts

  • Martina Živná received the Czech Minister of Health Award for Medical Research and Development in 2025 for her successful project Identification and Characterization of Genetic Factors of Hereditary Tubulointerstitial Kidney Disease II.
  • Multiomics Workshop in BIOCEV
  • Extracellular vesicles as precision therapeutics for psychiatric conditions: targeting interactions among neuronal, glial, and immune networks
  • Novel structure motif for the selective inhibition of TET1 protein based on perimidines
  • The potential of exosomes in regenerative medicine and in the diagnosis and therapies of neurodegenerative diseases and cancer

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The MULTIOMICS_CZ project is supported by programme Johannes Amos Comenius, Ministry of Education, Youth and Sports of the Czech Republic,
ID Project CZ.02.01.01/00/23_020/0008540 – Co-funded by the European Union.

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